Figure 1. Case presentation of patient 138T with muscle-invasive bladder cancer and validation of patient-derived tumor tissue.

(A) Computed tomography (CT) scan of the pelvis indicates a large bladder tumor invading the base of the bladder of patient 138T. The bladder is visible at the bottom center of the scan. The arrow indicates the tumor region. The tumor tissue appears as cloudy material within the bladder, whereas the remaining area in the bladder is eclipsed. (B) Representative images of hematoxylin/eosin (H&E) and immunohistochemistry staining of BD-138T tumor tissue with antibodies for the indicated proteins. CK7, cytokeratin 7; pan-CK, pan-cytokeratin; CK20, cytokeratin 20. Scale bars: 100 μm (Top), 20 μm (Bottom).