Figure 7. Imipramine blue (IB) acts as a PAD in 32D-BCR-ABL cells.
PP2A phosphatase activity (pmole phosphate/min) was assessed in untreated 32D-BCR-ABL cells and upon 6 h exposure to IB at concentration of 5 μM. The PAD, FTY720 (2.5 μM), was included as a positive control. Student's t tests were performed using GraphPad Prism version 6.0a with a P value < 0.05 being considered significant.