Figure 3. Cellular ATP levels and in vitro tumor cell invasion.

(A) ATP levels in tumor cells were sharply suppressed by chloramphenicol in a dose-dependent manner. (B) Chloramphenicol-induced ATP inhibition was much weaker in normal PBMCs than MM cells. The results are expressed as the mean ± SEM (error bars) for four separate experiments; *P < 0.05. (C) Transwell in vitro invasion assays indicate that chloramphenicol had almost no effect on the invasiveness of MM cells after 48 h of treatment (2.5 × 10⁴ tumor cells per well). The results are expressed as the mean ± SEM (error bars) for four separate experiments; * P < 0.05.