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. 2016 Jul 11;7(32):52207–52217. doi: 10.18632/oncotarget.10537

Figure 2. In vivo antitumor effect of F-PLP/pIL15 and pIL15 expression.

Figure 2

a. Tumor images; b. tumor nodules; and c. tumor weight analysis. d. Serum and e. ascite IL15 expression in tumor-bearing mice. f. The spleen cell-mediated cytotoxicity evaluation by a 51Cr release assay. As a result, the spleen cell-mediated cytotoxicity was in concordance with the expression of IL15. (**P < 0.01, ***P < 0.001, versus NS; ‡P < 0.05, ‡‡P < 0.01, ‡‡‡P < 0.001, versus PLP/pc3.1; §§P < 0.01, §§§P < 0.001, versus F-PLP/pc3.1; †P < 0.05, ††P < 0.01, versus PLP/pIL15; mean ± SD, n = 3 or 5).