Skip to main content
. 2016 Jul 20;7(32):52375–52391. doi: 10.18632/oncotarget.10737

Figure 2. Photomicrographs of human breast carcinoma.

Figure 2

(A–F) and lung adenocarcinoma (G–L) brain metastasis resections stained immunohistochemically against LFA-1 (A–B and G–H) and ICAM-1 (C and I); higher magnification images from boxes shown in D–F and J–L. Scale bars = 50 μm. Widespread expression of LFA-1 is evident on tumour cells (brown staining; arrows, D and J) whilst ICAM-1 is evident on the intersection between tumour cells and brain parenchyma (brown staining; arrows, F and L). Immunofluorescence images of human breast cancer brain metastasis (B, E) and lung adenocarcinoma brain metastasis (H, K) demonstrate co-localisation (arrows) of LFA-1 (red) with tumour cells (blue; DAPI nuclear stain). Surrounding astrocytes stained green. Scale bar = 50 μm.