Table 1. Cancers, genes, mutations, and CRISPRs editing ability.

Cancers/ Genetic diseases	Mutations that can be corrected with CRISPR/Cas9*	CRISPR/Cas9 Gene targets	References
Lung	exon 19 deletion and L858R	EGFR	[11]
Breast	G309A, D769H, D769Y, V777L, P780ins, V842I, and R896C and BRCA1/2 mutations	HER2/Neu, BRCA	[12]
Thyroid	C228T and C250T	TERT promoter	[13]
β- Thalesemia	IVS2-654 (C > T)	HBB	[14]
Huntington	p.(Gln302) and p.(Tyr539Cys)	RNF216	[15]
Limb girdle muscular dystrophies types 2B and 2D	c.5713C>T; p.R1905X, and missense c.229C>T; p.R77C	Dysferlin, and alpha-sarcoglycan	[16]
Alzheimer's	H214N, R220P	Presenilin 1	[17]

^*These are only few of the representative mutations causing cancers or other genetic diseases