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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Behav Brain Res. 2016 Dec 16;320:316–322. doi: 10.1016/j.bbr.2016.12.016

Figure 2.

Figure 2

Changes in the average daily ethanol intake and water consumption following oral gavage of Augmentin in P rats exposed to free choice of ethanol and water for 5 weeks. A) Effect of Augmentin treatment on average daily ethanol intake as compared to control (g/kg/day) in P rats. Two-way repeated measure ANOVA followed by Bonferroni multiple comparisons post-hoc test revealed a significant reduction in ethanol consumption in Augmentin group as compared to control group starting 48 hours after the first day of treatment (p<0.001). B) Effect of oral gavage of Augmentin on percent of ethanol preference in male P rats. Two-way repeated measure ANOVA followed by Bonferroni multiple comparisons post-hoc test revealed a significant decrease in ethanol preference in oral gavage of Augmentin group from Day 2 through Day 5 as compared to the control group. C) Effect of Augmentin treatment on water consumption as compared to control group (g/kg/day). Two-way repeated measure ANOVA followed by Bonferroni multiple comparisons post-hoc test revealed a significant increase in water intake in all rats treated with Augmentin (p<0.001) as compared to the control group from Day 2 throughout Day 5. D) Effect of oral gavage of Augmentin on average body weight of P rats. Two-way repeated measure ANOVA followed by Bonferroni multiple comparisons post-hoc test showed no significant difference in average body weight between the Augmentin treatment and control groups. Data are represented as mean ± SEM (**p<0.01, ***p<0.001, ****p<0.0001), (n=7 for each group).