TABLE 2.

General linear model examining the relationship between candidate predictors and overall acute pain severity following Motor Vehicle Collision (n = 922) and sexual assault (n = 80).

	Motor Vehicle Collision		Sexual Assault
Variablea	F	p value	F	p value
Age	3.83	0.051	<0.001	0.999
Sex	0.037	0.947	N/A	N/A
Peritraumatic distressb	34.19	<0.001	0.011	0.918
rs3750625c	3.224	0.073	5.432	0.007
rs3750625 * sex	0.102	0.750	N/A	N/A
rs3750625 * distress	4.103	0.043	5.467	0.007

^astudy site was also included as a categorical variable

^bFor the MVC cohort distress was assessed in the Emergency Department using the Peritraumatic Distress Inventory[11], For the sexual assault cohort distress was assessed using the Acute Stress Disorder Questionnaire[13].

^cDominant genetic model used for rs3750625