Table 3.
Relative risk for adverse health status outcomes by treatment decade and by demographic characteristics and health habits among survivors.
| Poor General Health | Functional Impairment | Activity Limitation | Poor Mental Health | Cancer-related Pain | Cancer-related Anxiety | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | % | RR (95% CI) | % | RR (95% CI) | % | RR (95% CI) | % | RR (95% CI) | % | RR (95% CI) | % | RR (95% CI) | ||
| Treatment decade | 1970-1979 | 4618 | 11.2 | 1.0 | 12.8 | 1.0 | 12.8 | 1.0 | 17.5 | 1.0 | 9.6 | 1.0 | 13.3 | 1.0 |
| 1980-1989 | 4669 | 11.8 | 1.2 (1.0, 1.4) | 12.2 | 1.1 (0.9, 1.2) | 11.6 | 0.9 (0.8, 1.0) | 17.3 | 1.0 (0.9, 1.1) | 10.6 | 1.1 (1.0, 1.3) | 14.0 | 1.0 (0.9, 1.1) | |
| 1990-1999 | 5279 | 13.3 | 1.3 (1.1, 1.5) | 11.3 | 1.0 (0.9, 1.2) | 11.9 | 1.0 (0.9, 1.2) | 17.8 | 1.0 (0.9, 1.1) | 11.3 | 1.3 (1.1, 1.5) | 14.4 | 1.0 (0.9, 1.1) | |
| Sex | Male | 7492 | 11.5 | 1.0 | 11.0 | 1.0 | 9.6 | 1.0 | 16.6 | 1.0 | 9.7 | 1.0 | 11.0 | 1.0 |
| Female | 7074 | 13.0 | 1.3 (1.1, 1.4) | 13.0 | 1.6 (1.4, 1.7) | 14.7 | 1.9 (1.7, 2.1) | 18.6 | 1.1 (1.0, 1.2) | 11.7 | 1.3 (1.2, 1.5) | 17.2 | 1.5 (1.4, 1.7) | |
| Non-Hispanic white | Yes | 12062 | 11.2 | 1.0 | 11.4 | 1.0 | 11.7 | 1.0 | 17.1 | 1.0 | 10.3 | 1.0 | 13.9 | 1.0 |
| No | 2504 | 17.1 | 1.7 (1.5, 1.9) | 14.7 | 1.3 (1.2, 1.5) | 13.8 | 1.3 (1.1, 1.4) | 19.6 | 1.2 (1.1, 1.3) | 12.2 | 1.2 (1.1, 1.4) | 14.6 | 1.1 (1.0, 1.2) | |
| Smoking status | Never | 9936 | 9.7 | 1.0 | 10.8 | 1.0 | 10.9 | 1.0 | 14.2 | 1.0 | 8.5 | 1.0 | 11.9 | 1.0 |
| Former | 2074 | 13.1 | 1.4 (1.2, 1.6) | 11.8 | 1.2 (1.0, 1.4) | 13.8 | 1.2 (1.1, 1.4) | 19.3 | 1.4 (1.2, 1.5) | 12.7 | 1.4 (1.2, 1.6) | 17.5 | 1.4 (1.2, 1.5) | |
| Current | 2472 | 21.9 | 2.8 (2.5, 3.1) | 16.9 | 1.8 (1.6, 2.1) | 14.9 | 1.5 (1.3, 1.7) | 29.7 | 2.1 (1.9, 2.2) | 17.2 | 2.2 (2.0, 2.5) | 19.4 | 1.6 (1.4, 1.7) | |
| Heavy drinking* | No | 12252 | 12.1 | 1.0 | 12.7 | 1.0 | 12.2 | 1.0 | 16.9 | 1.0 | 10.4 | 1.0 | 12.9 | 1.0 |
| Yes | 2311 | 13.2 | 0.9 (0.8, 1.1) | 8.7 | 0.5 (0.4, 0.6) | 11.5 | 0.7 (0.6, 0.8) | 20.7 | 1.1 (1.0, 1.2) | 11.9 | 1.0 (0.8, 1.1) | 19.6 | 1.2 (1.0, 1.3) | |
| Body mass index† | Normal | 7129 | 8.5 | 1.0 | 10.0 | 1.0 | 10.2 | 1.0 | 15.9 | 1.0 | 8.9 | 1.0 | 13.6 | 1.0 |
| Underweight | 758 | 16.3 | 2.0 (1.6, 2.5) | 19.7 | 2.1 (1.7, 2.6) | 19.7 | 2.1 (1.7, 2.5) | 20.4 | 1.3 (1.1, 1.5) | 14.1 | 1.8 (1.4, 2.2) | 14.9 | 1.1 (0.9, 1.3) | |
| Overweight | 3905 | 11.2 | 1.3 (1.2, 1.5) | 10.4 | 1.0 (0.9, 1.2) | 11.3 | 1.1 (1.0, 1.3) | 17.2 | 1.1 (1.0, 1.2) | 10.7 | 1.2 (1.1, 1.4) | 12.8 | 1.0 (0.9, 1.1) | |
| Obese | 2394 | 22.3 | 2.7 (2.4, 3.1) | 17.2 | 1.7 (1.5, 1.9) | 15.9 | 1.5 (1.3, 1.7) | 22.0 | 1.3 (1.2, 1.5) | 14.3 | 1.5 (1.3, 1.8) | 16.6 | 1.2 (1.1, 1.3) | |
| Meets physical activity guidelines‡ | Yes | 5777 | 7.8 | 1.0 | 9.1 | 1.0 | 8.4 | 1.0 | 15.5 | 1.0 | 9.6 | 1.0 | 13.7 | 1.0 |
| No | 8348 | 15.3 | 1.9 (1.7, 2.2) | 13.9 | 1.4 (1.3, 1.6) | 14.7 | 1.7 (1.5, 1.9) | 19.1 | 1.2 (1.1, 1.3) | 11.3 | 1.1 (1.0, 1.2) | 14.2 | 1.0 (0.9, 1.0) | |
N=number, %=percent, RR=relative risk, CI=confidence interval
Regression models used a binomial distribution with a log link. Adjusted for sampling weights, attained age and survival time in years which were not significant.
*
Consuming > 4 drinks/day or > 14 drinks/week for males and consuming > 3 drinks/day or > 7 drinks/week for females,
†
Underweight: <18.5 kilograms/square meter (kg/m2), Normal: 18.5-24.9 kg/m2, Overweight: 25-29.9 kg/m2, Obese: ≥30kg/m2.
‡
≥150 minutes of moderate or 75 minutes of vigorous physical activity per week.
Bold text indicates RR estimates with p < 0.05