Table 1.

Common dimorphisms of the KIR2DL5 coding and promoter regions.

		Representative alleles
Locus	Promoter nucleotide -97	Asn152-Gly174	Asp152-Ser174
KIR2DL5A	G	*001	*005
KIR2DL5B	A/Ga	*006	*002

Guanidine at nucleotide -97 correlates with clonal transcription; adenosine with complete silencing; Asn152-Gly174 and Asp152-Ser174 with cell surface and intracellular expression, respectively.

^aEach of KIR2DL5B*006 and *002 comprises multiple alleles coding for identical polypeptides, but differing from each other by changes in nucleotide -97 (besides other non-coding or synonymous substitutions) (13).