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. 2017 Jan 17;7:681. doi: 10.3389/fimmu.2016.00681

Figure 1.

Figure 1

BRILIA flowchart with examples and rationales for each step. For the sample sequences in the middle, the V, NVD, D, NDJ, and J segments are separated by a space, where a double space indicates a lack of N region (e.g., NDJ is absent initially). A lowercase letter is either an N nucleotide (nt) or a mismatched nt with respect to the germline genes, and a bolded letter is a consensus mismatched nt.