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. 2017 Jan 17;7:681. doi: 10.3389/fimmu.2016.00681

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Copyright © 2017 Lee, Khavrutskii, Wallqvist, Bavari, Cooper and Chaudhury.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Somatic hypermutations (SHM) in CDR3 and V framework regions. Comparison of the mutations accumulated in the CDR3 versus V framework (Vframe) regions, as determined by (A) the standard method and (B) BRILIA.