Table 3.
Selected genes in relevant biological processes
| Biological process/gene name | Symbol | Fold change | FDR |
|---|---|---|---|
| Neutrophil function | |||
| Azurocidin 1 (cationic antimicrobial protein 37) | AZU1a | 1.57 | 0.001 |
| Catalase | CATa | 3.51 | 0.000 |
| Cathepsin D | CTSD | 2.00 | 0.007 |
| CD177 | CD177a | 3.49 | 0.000 |
| Formyl peptide receptor 1 | FPR1 | 2.26 | 0.000 |
| Grancalcin, EF-hand calcium binding protein | GCAa | 2.79 | 0.000 |
| Lactotransferrin | LTFa | 2.82 | 0.000 |
| Leukotriene A4 hydrolase | LTA4H | 2.34 | 0.003 |
| Myeloperoxidase | MPO | 2.24 | 0.000 |
| Neutrophil cytosolic factor 2 (65 kDa, chronic granulomatous disease, autosomal 2) | NCF2 | 2.08 | 0.004 |
| Peptidoglycan recognition protein 1 | PGLYRP1a | 2.42 | 0.000 |
| Phospholipid scramblase 1 | PLSCR1a | 2.55 | 0.000 |
| S100 calcium binding protein A8 (calgranulin A) | S100 A8 | 2.07 | 0.001 |
| S100 calcium binding protein A9 (calgranulin B) | S100 A9 | 2.14 | 0.001 |
| S100 calcium binding protein A12 (calgranulin C) | S100 A12 | 2.42 | 0.000 |
| S100 calcium binding protein P | S100P | 2.55 | 0.000 |
| Natural killer cell function | |||
| Killer cell lectin-like receptor subfamily B, member 1 | KLRB1 | −1.75 | 0.069 |
| Killer cell lectin-like receptor subfamily C, member 2 | KLRC2a | −1.64 | 0.030 |
| Killer cell lectin-like receptor subfamily D, member 1 | KLRD1 | −1.83 | 0.053 |
| Granulysin | GNLYa | −2.48 | 0.001 |
| C-type lectin domain family 1, member B | CLEC1B | −1.70 | 0.036 |
| Solute carrier family 30 (zinc transporter), member 1 | SLC30A1 | −1.89 | 0.071 |
| Zinc finger, CCHC domain containing 2 | ZCCHC2a | −2.14 | 0.010 |
| Zinc finger E-box binding homeobox 1 | ZEB1 | −1.72 | 0.007 |
| Zinc finger protein 839 | ZNF839 | −1.72 | 0.089 |
| Zinc finger protein 671 | ZNF671a | −2.69 | 0.000 |
| T cell function | |||
| Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | CEACAM1 | 1.78 | 0.032 |
| Chemokine (C-X-C motif) receptor 4 | CXCR4a | 1.69 | 0.022 |
| Hematopoietic cell-specific Lyn substrate 1 | HCLS1a | 2.21 | 0.002 |
| Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | ITGB1 | 1.97 | 0.045 |
| Interferon gamma receptor 2 (interferon gamma transducer 1) | IFNGR2a | 1.88 | 0.004 |
| Interleukin 10 | IL10 | 1.71 | 0.022 |
| Protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | PTPN22 | 2.33 | 0.003 |
| Protein tyrosine phosphatase, receptor type, C | PTPRCa | 2.30 | 0.001 |
| Transcription | |||
| Hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | HIF1A | 1.75 | 0.055 |
| CCAAT/enhancer binding protein (C/EBP), beta | CEBPBa | 2.35 | 0.000 |
| CCAAT/enhancer binding protein (C/EBP), alpha | CEBPA | 2.10 | 0.002 |
| B-cell CLL/lymphoma 6 | BCL6 | 2.00 | 0.017 |
| CREB binding protein | CREBBP | −1.95 | 0.023 |
| GATA binding protein 3 | GATA3a | −1.84 | 0.043 |
aSignificant in Rank Products and SVA