Table 4.
Relative proportions of CD4+ and CD8+ cells of total lymphocytes and total counts in peripheral systemic blood of cows fed diets with increasing concentrations of Fusarium toxins (LSMEANS, n = 10)
| Fusarium toxins (DON/ZEN, mg/kg at 88 % DM) | Week | CD4+ [%] | CD8+ [%] | CD4+/CD8+ | CD4+ [G/l] | CD8+ [G/l] | |
|---|---|---|---|---|---|---|---|
| CON | 0.06/0.02 | 3 | 25.0 | 11.3 | 3.8 | 0.9 | 0.4 |
| 0.06/0.02 | 10 | 25.8 | 12.3 | 2.2 | 0.8 | 0.5 | |
| 0.06/0.02 | 14 | 28.5 | 15.7 | 1.8 | 1.0 | 0.5 | |
| TOX-1 | 2.31/0.29 | 3 | 25.9 | 12.0 | 2.3 | 0.9 | 0.4 |
| 2.31/0.29 | 10 | 30.3 | 12.9 | 2.5 | 0.9 | 0.4 | |
| 2.31/0.29 | 14 | 26.7 | 11.2 | 2.1 | 0.7 | 0.3 | |
| TOX-2 | 4.61/0.58 | 3 | 23.9 | 12.1 | 3.1 | 0.9 | 0.5 |
| 4.61/0.58 | 10 | 27.9 | 13.9 | 2.0 | 1.1 | 0.6 | |
| 4.61/0.58 | 14 | 16.2 | 9.9 | 1.8 | 1.0 | 0.5 | |
| p values | |||||||
| DON/ZEN | 0.020 | 0.793 | 0.888 | 0.650 | 0.110 | ||
| Week | 0.061 | 0.457 | 0.098 | 0.827 | 0.866 | ||
| DON/ZEN x week | 0.020 | 0.043 | 0.632 | 0.146 | 0.720 | ||
| Paritya | 0.513 | 0.772 | 0.346 | 0.581 | 0.750 | ||
| Diseasedb | 0.051 | 0.869 | 0.656 | 0.955 | 0.902 | ||
| PSEM | 2.2 | 1.7 | 0.8 | 0.1 | 0.5 | ||
LSMEANS least square means, PSEM pooled standard error of means
aCows were classified as primi- and pluriparous cows
bCows were classified as diseased or not diseased