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. 2017 Jan 17;11:1. doi: 10.3389/fnana.2017.00001

Table 2.

Number of permutations and corresponding lowest possible p -value depending on the group size assuming the groups to be equal in size.

Number of animals per group (equal group size) Number of permutations Lowest p -value
3 20 0.0500
4 70 0.0143
5 252 0.0040
6 924 0.0011
7 3432 0.0003
8 12870 7.77e-05
9 48620 2.06e-05
10 184756 5.41e-06

Increasing the number of animals exponentially increases the computational burden.