Table 1.
Variable | Chronic HCV (n = 437) | Liver cirrhosis (n = 88) | HCC (n = 38) | Healthy control (599) | p a value |
---|---|---|---|---|---|
Age (yrs.) | 43.23 ± 22.25 | 53.20 ± 19.79 | 63.23 ± 10.70 | 30.79 ± 8.90 | <0.0001 |
Sex | |||||
Male count (%) | 214 (49%) | 44 (50%) | 18 (47.4%) | 577 (96.3%) | <0.0001 |
Female count (%) | 223 (51%) | 44 (50%) | 20 (52.6%) | 22 (3.7%) | |
BMI^∗ | 29.2 (25.67–33.39) | 30.06 (26.22–33.06) | 25.99 (21.89–31.39) | 0.804 | |
Platelet (per 109/L)∗ | 230 (178.75–282.25) | 163.5 (108.50–205.50) | 104.00 (51.50–139.00) | <0.0001 | |
ALT∗∗ | 87.58 ± 119.76 | 93.18 ± 68.88 | 114.33 ± 31.78 | 0.738 | |
AST∗∗ | 55.36 ± 41.87 | 77.28 ± 47.20 | 91.33 ± 24.58 | <0.0001 | |
ALP∗∗ | 113.37 ± 78.91 | 133.66 ± 90.04 | 147.00 ± 96.70 | 0.072 | |
HCV viral Load (log10)∗ | 6.04 (5.42–6.53) | 6.08 (5.57–6.45) | 5.98 (2.79–7.24) | 0.552 |
∗Values are expressed as median interquartile range (25th–75th). ∗∗Values are expressed as mean ± SD.
p a: nonparametric test and one-way ANOVA for continuous data and Chi square test for categorical data.
ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase.