Table 5. Secondary comparative outcomes (difference in differences [DiD]) for pharmacotherapy.
Outcome measure (secondary) | t1 | t2 | t2 vs t1 | DiD | ||||
Pharmacotherapy | IG (SD) |
CG (SD) |
IG (SD) |
CG (SD) |
IG | CG | Absolute intervention effect*3 (p-value [95% CI]) |
Relative change*4 % |
Number of drug prescriptions per patient*1 | 26.4 (23.2) |
26.8 (23.4) |
28.8 (24.0) |
29.1 (24.0) |
2.4 | 2.3 | 0.1 (0.156 [−0.04; 0.28]) |
0.4 |
Number of different medications (ATC-7) per patient*1 |
7.67 (5.48) |
7.67 (5.62) |
8.14 (5.66) |
8.09 (5.90) |
0.48 | 0.42 | 0.06 (0.035 [0.004; 0.11]) |
0.7 |
Share of patients with 5 or more different medications (GP prescriptions. ATC-7)*2 |
57.2% | 55.9% | 61.3% | 58.4% | 4.1*5 | 2.6*5 | 1.15 (<0.001 [1.11; 1.19]) |
15 |
p<0.05. statistically significant difference (t-test respectively chi square test); *1 binary variable; *2 metric variable; *3 intervention effect for metric variables: mean difference; intervention effect for binary variables: odds ratio; *4 relative change for metric variables: share of intervention effect in IG t1 in %; relative change for binary variables: odds ratio –1. i.e. percentage change in odds;
*5 percentage points; ATC. anatomical therapeutic chemical classification system [full 7-digit form of ATC codes];
IG. intervention group; CG. control group; CI. confidence interval; SD. standard deviation