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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Clin Pharmacol. 2016 Jun 26;57(1):64–76. doi: 10.1002/jcph.775

Figure 4.

Figure 4

Predicted morphine concentrations at different continuous morphine infusion rates by birthweight. Each boxplot represents steady-state concentrations from 1000 simulated neonates with HIE receiving hypothermia. Outliers are not presented. Dashed lines reference target concentrations between 10 to 40 ng/ml.