Table 1.
Patient Demographics (n = 20)
| Median or No. |
IQR | Min, Max | |
|---|---|---|---|
|
| |||
| Gestational Age, wks | 39.1 | 37.2 – 40.4 | 36.0, 41.3 |
|
| |||
| Birthweight, kg | 3.50 | 3.03 – 3.71 | 1.82, 5.3 |
|
| |||
| Female, n (%) | 13 (65%) | ||
|
| |||
| Race / Ethnicity, n (%) | |||
| White | 9 (45%) | ||
| Hispanic | 8 (40%) | ||
| Asian | 3 (15%) | ||
|
| |||
| APGAR | |||
| 5 min | 4 | 2 – 6 | 0, 8 |
| 10 min | 6 | 5 – 7 | 0, 8 |
|
| |||
| First arterial or capillary pH | 6.9 | 6.9 – 7.1 | 6.6, 7.2 |
|
| |||
| Base Deficit, mmol/L | −18 | −15 – −20 | −12, −25 |
|
| |||
| Crmax, mg/dL | 1.1 | 0.8 – 1.3 | 0.5, 2.0 |
|
| |||
| ALTmax, U/L | 32 | 18 – 78 | 15, 558 |
|
| |||
| ALTmax >100 U/L, n (%) | 3 (15%) | ||
|
| |||
| Temperature core, °C | 33.5 | 33.4 – 33.7 | 33.1, 33.7 |
|
| |||
| Assisted Ventilation, n (%) | 14 (70%) | - | - |
|
| |||
| Seizures, n (%) | 4 (20%) | - | - |
|
| |||
| Dopamine, n (%) | 6 (30%) | - | - |
|
| |||
| Death, n (%) | 1 (5%) | - | - |
IQR, Interquartile range; Crmax, maximum serum creatinine during hypothermia; ALTmax, maximum alanine aminotransferse during hypothermia; Temperature core, esophageal temperature at time of pharmacokinetic sampling.