Figure 1. Maternal diabetes impairs enamel formation in offspring.

(A) Micro-computed tomography (CT) analysis of incisors from the offspring of control and diabetic dams at three and six weeks of age. A1: Diagram of micro CT scanning of mandibular incisors. The perpendicular cutting plane, from root to tip along the three-dimensional incisor, was used to measure the enamel area, and two panels, representative of different sites, are shown in plane 1 and plane 2. Plane 1′ is a magnified view of plane 1. Enamel is coloured red, and dentin is coloured green. A2 and A3: Micro CT scan of incisors from offspring of control and diabetic dams at three weeks (A2) and six weeks (A3) of age. Arrows indicate the enamel area. (B–E) Measurements of the cross-sectional area of enamel (B: three weeks; D: six weeks) and mineral density (C: three weeks; E: six weeks) are presented as means. *P < 0.05 vs. control.