Table 1. Diagnostic Performance of Galactomannan, β-D-glucan and Nested-PCR in Patients with Proven or Probable Invasive Fungal Infections Documented by Culture.
Case No. | EORTC/MSG | GM, ng/mL | BDG, pg/mL | Site of Infection | Culture Result | PCR Result |
---|---|---|---|---|---|---|
1 | Proven | 0.111 | 77 | Blood | Candida tropicalis | _ |
2 | Proven | 0.108 | 85 | Blood | C. albicans | + |
3 | Proven | 0.500 | 112 | Sinus/biopsy | Aspergillus flavus | + |
4 | Probable | 0.545 | 65 | Lung/bronchial washing | A. flavus | + |
5 | Probable | 0.530 | 192 | Lung/bronchial washing | A. fumigatus | + |
6 | Probable | 0.915 | 95 | Lung/bronchial washing | A. flavus | + |
7 | Probable | 0.300 | 50 | Sinus/sinus washing | A. fumigatus | _ |
8 | Probable | 1.154 | 110 | Lung/bronchial washing | Aspergillus spp. | + |
9 | Probable | 0.610 | 74 | Lung/bronchial washing | A. flavus | + |
10 | Probable | 0.598 | 125 | Lung/bronchial washing | A. fumigatus | _ |
11 | Probable | 1.790 | 72 | Lung/bronchial washing | A. fumigatus | + |
12 | Probable | 0.841 | 55 | Lung/bronchial washing | A. fumigatus | + |
13 | Probable | 0.147 | 119 | BAL | C. albicans | + |
14 | Probable | 0.108 | 113 | BAL | C. albicans | + |
15 | Probable | 0.112 | 130 | Sputum | C. albicans | + |
16 | Probable | 0.147 | 340 | FUO | C. tropicalis | _ |
17 | Probable | 0.200 | 132 | FUO | C. albicans | + |
18 | Probable | 0.154 | 128 | FUO | C. albicans | + |
Abbreviations: BAL, bronco-alveolar lavage; EORTC/MSG, European organization for research and therapy of cancer and mycoses study group; FUO, fever of unknown origin; PCR, polymerase chain reaction.