Table 3.
Frequency of PIK3CA mutations in classic lobular carcinoma in situ (LCIS)/invasive lobular cancer (ILC)
| Mutation (total number of cases) | Pure LCIS (27) | inv-LCIS (28) | ILC (25) |
|---|---|---|---|
| PIK3CA_pH1047R_c3140A_G | 3 (1558,1717, 04078a) | 3 (1731, 1965, 1604) | 2a (1731,1604) 1965- no tissue left |
| PIK3CA_pH1047R_c3140A_T | 0 | 0 | 0 |
| PIK3CA_pE542K_c1624G_A | 1 (1339) | 3 (1063,1604, 1640) | 3 (1063, 1604, 1640) |
| PIK3CA_pE545K_c1636C_A | 0 | 0 | 0 |
| PIK3CA_pE545K_c1633G_A | 1 (1078) | 2 (1270, 1604) | 2 (1270,1126) |
| Total number of cases with PIK3CA Mutations | 5 | 6 | 6 |
asample IDs (italics represent samples with multiple PIK3CA mutations)