Fig. 2.

Co-inertia analysis of urine-derived metabolomic and 16S rRNA gut microbiota data from stool. Microbiota data was scalar normalised and logged. Microbiota is represented by circles and the metabolomic samples are represented by squares. Four groups are visualised; preterm-Caesarean section (blue), preterm-spontaneous vaginal delivery (orange), full-term Caesarean section (red) and full-term spontaneous vaginal delivery (green). Small objects represent the individual samples and large objects represent the barycentre of the group. Analysis shows that the co-variance between the microbiota and metabolomics dataset splits the preterm infants from the full-terms. Metabolites associated with this split are highlighted in Additional file 3: Figure S1 and Additional file 1: Table S4