Table 2. Univariate and multivariate cox-proportional regression analyses for the factors predicting biochemical recurrence after radical prostatectomy.
| Variable | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Age | 0.989 (0.951–1.028) | 0.568 | 0.974 (0.938–1.012) | 0.175 |
| Preoperative PSA | 0.998 (0.989–1.006) | 0.573 | 0.992 (0.982–1.003) | 0.147 |
| ADC group | <0.001 | 0.002 | ||
| Group B | 1 | 1 | ||
| Group A | 3.744 (1.785–7.851) | 3.238 (1.516–6.915) | ||
| Pathologic GS | 0.461 | 0.915 | ||
| ≤7 | 1 | 1 | ||
| ≥8 | 1.204 (0.735–1.973) | 0.972 (0.584–1.621) | ||
| Pathologic stage | 0.018 | 0.126 | ||
| ≤T2 | 1 | 1 | ||
| ≥T3 | 1.836 (1.111–3.034) | 1.542 (0.885–2.686) | ||
| Positive surgical margin | 1.583 (0.981–2.552) | 0.060 | 1.108 (0.663–1.850) | 0.696 |
| Pathologic LN positive | 2.563 (1.477–4.449) | 0.001 | 2.242 (1.228–4.091) | 0.009 |
Group A, patients with ADC values <746×10−6 mm2/s; group B, patients with ADC values ≥746×10−6 mm2/s.; ADC, apparent diffusion coefficient; HR, hazard ratio; CI, confidence interval; PSA, prostate-specific antigen; ADC, apparent diffusion coefficient; GS, Gleason score; LN, lymph node.