Table 2.
Clinicopathological and miR-141 correlation of the expression of an ovarian cancer tissue array (OVC1021). The 5-fold cut-off was determined by ROC analysis
| Parameters | n(=97) | KLF12 expression | ||
|---|---|---|---|---|
| ≤5-fold | >5-fold | p | ||
| Grade | ||||
| Low (1 + 2) | 50 | 25 (50%) | 25 (50%) | |
| High (3) | 46 | 24 (52%) | 22 (48%) | 0.841 |
| Stage | ||||
| Early (1) | 48 | 14 (29%) | 34 (71%) | |
| Late (2 + 3) | 49 | 36 (73%) | 13 (27%) | 0.000* |
| Metastasis | ||||
| Yes | 24 | 18 (75%) | 6 (25%) | |
| No | 73 | 32 (44%) | 41 (56%) | 0.010* |
| miR-141 | ||||
| ≤ 5 folds | 50 | 14 (28%) | 36 (72%) | |
| > 5 folds | 48 | 37 (77%) | 11 (23%) | 0.000* |
*P < 0.05