Table 1. Characteristics of Study Subjects Analyzed.
| Before Treatment | After Treatment | |
|---|---|---|
| Patients included (n = 18) | ||
| Age, years (mean ± SD) | 25.8 ± 7.9 | 27.1 ± 7.8 |
| Gender (M:F), patient number | 13:5 | 13:5 |
| Body mass index, kg/m2 (mean ± SD) | 20.4 ± 3.2 | 22.5 ± 3.4 |
| CDAI (mean ± SD) | 194.3 ± 143.3 | 71.7 ± 66.4 |
| ESR, mm/hr (mean ± SD) | 50.7 ± 29.8 | 23.6 ± 25 |
| CRP, mg/dL (median [range]) | 2.3 (0.33–12.73) | 0.21 (0.1–7.29) |
| Index lesions analyzed (n = 37)* | ||
| Number of lesions | 37 | |
| TI, Rt, T, D, S, R | 12, 12, 3, 6, 3, 1 | |
| Endoscopic response to therapy | ||
| Complete remission | 14 | |
| Reduced inflammation | 19 | |
| Unchanged inflammation | 3 | |
| Increased inflammation | 1 | |
| CDMI score (mean ± SD)† | 5.7 ± 1.9 | 2.3 ± 2.5 |
*Data indicate number of lesions unless specified otherwise, †Crohn's disease MRI activity index was calculated according to method that was previously validated (29,30). CDAI = Crohn's disease activity index, CDMI = Crohn's disease MRI activity index, CRP = C-reactive protein, D = descending colon, ESR = erythrocyte sedimentation rate, R = rectum, Rt = right colon (including cecum and ascending colon), S = sigmoid colon, T = transverse colon, TI = terminal ileum