RSL phenolics are bioaccessible in TIM-1 model. RSL was introduced to TIM-1 in fed state. Chlorogenic acid (A), quercetin 3-glucoside (B), and quercetin malonyl-glucoside (C) bioaccessibility (mean ± SD of 3 independent runs) as a percent of input was determined in filtrates collected from jejunum, ileum, and efflux compartments at 1, 2, 3 and 4 h after start of digestion. Phenolics were quantified by UPLC-UV.