Table 4.

ADCC Activity of antibodies against H1975 lung cancer cell line. Average ± SEM of Emax (% compared to complete lysis) and EC₂₀ (the interpolated antibody concentration needed to elicit 20% lysis) for different antibodies.

	Emax (%)		EC20 (nM)
	Average	±SEM	Average	±SEM
JNJ-61186372 - LF	59	5.38	0.0015	0.0007
c-Met x inert arm - LF	39	1.12	0.0528	0.0172
EGFR x inert arm - LF	58	4.50	0.0051	0.0012
JNJ-61186372 - NF	40	1.48	0.1505	0.1052

NF = normal levels of core fucosylation; LF = low levels of core fucosylation.