Table 4.

Radiation absorbed dose projections for ⁶⁴Cu-NOTA-pertuzumab F(ab')₂ in humans^*.

Organ	Equivalent dose (mSv/MBq)
Brain	0.001
Breasts	0.002
Gallbladder wall	0.015
Small intestine	0.011
Lower large intestine	0.282
Heart wall	0.019
Kidneys	1.070
Liver	0.092
Lungs	0.010
Muscle	0.009
Ovaries	0.025
Pancreas	0.016
Spleen	0.068
Total body	0.015

^*Radiation absorbed dose projections in humans were based on the cumulative number of disintegrations (N) in source organs in mice obtained from biodistribution studies and were estimated using OLINDA Ver. 1.0 software. This assumes that the relative organ biodistribution of ⁶⁴Cu-NOTA-pertuzumab F(ab')₂ in humans will be the same as that in mice.