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Production yields of MATCH protein variants and a parental, rabbit IgG after chromatography and dialysis. The MATCH proteins and rIgG were expressed by transient gene expression in CHO and purified by similar methods.
| Protein | Weight (Da) | Yield (mg) per L expression volume | Molar equivalents |
|---|---|---|---|
| pMATCH | 106′822 | 3.4 | 0.18 |
| apMATCH | 105′219 | 12.1 | 0.65 |
| apMATCH-diS | 105′713 | 17.6 | 0.94 |
| anti-TNFα rIgG | 147′809 | 26.2 | 1 |
