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PDZ1i treatment combined with radiation in an in vivo model of GBM. (A) U1242-luc cells were injected intracranially into nude mice. After 7 d, mice were randomized to four groups, and mice receiving therapy were treated on days 11 to 14 as pictured. (B) Kaplan–Meier survival curves for each treatment group. Median survival is as listed. (C) Brain tissue was isolated and sectioned, and H&E staining is shown.
