Fig. S7.
Comparison of host immune response to inactivated WSN and WSN-NA viruses. Mice were immunized with inactivated viruses as indicated and mouse survival rate was then measured after challenge with a lethal dose of (A) WSN and (B) H5N1 viruses. (C) The titer of NA antibody was measured by neuraminidase inhibition assay. IC50 of sera from WSN virus-treated mice was 5.2 μg/mL, and WSN-NA virus was 4.7 μg/mL. (A and B) Ten independent experiments are shown. (C) Mean ± SEM for 10 independent experiments.