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Trypsin-susceptibility assay of Arbidol. SDS/PAGE analysis of the trypsin-susceptibility assay of Arbidol. Lane 1, acidified PR8 H1 HA treated with trypsin. Lane 2, PR8 HA treated with trypsin without prior acidification. Lane 3, acidified PR8-CR9114 Fab complex treated with trypsin (additional bands correspond to the Fab (∼50 kDa) and the heavy and light chains of the Fab (∼30 kDa). Lane 4, acidified PR8–Arbidol complex treated with trypsin.
