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Effect of BMS753 on Aβ42 aggregation. Kinetic profiles of the aggregation of a 2 μM Aβ42 solution in the absence and presence of either 1% DMSO (black) or 1 (blue), 3 (green), and 5 (purple) M eq of BMS753. BMS753, the structure of which is shown in an open circle, did not show any effect on the aggregation of Aβ42 similar to the results obtained with the dot-blot assay (Fig. 1).
