Fig. S9.
Analysis of the effects of set B molecules on Aβ42 aggregation kinetics in the presence of 1%, 2%, and 5% of preformed seed fibrils. (A–C) Kinetic profiles of the aggregation of a 2 μM Aβ42 solution in the presence of increasing concentrations of preformed fibril seeds in the presence of either 1% DMSO (gray) or 0.5 (red) and 5 (green) M eq of MM11253 (A, D, and G), adapalene (B, E, and H), and BMS493 (C, F, and I). Note the concentration-dependent effect of the set B molecules on the aggregation kinetics of Aβ42 under seeding conditions.
