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Effects of BMS753 on Aβ42 aggregation in 66% CSF. Kinetic profiles of the aggregation of a 2 μM Aβ42 solution in the absence and presence of either 1% DMSO (black) or 0.5 (cyan), 1 (blue), 3 (green), and 5 (purple) M eq of BMS753. BMS753 did not retard the aggregation of Aβ42 similar to the results obtained in phosphate buffer (Fig. S3).
