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Effects of representative molecules from sets A and B on Aβ42 aggregation in 66% CSF. Kinetic profiles of the aggregation of a 2 μM Aβ42 solution in the absence and presence of either 1% DMSO (black) or 0.5 (cyan), 1 (blue), 3 (green), and 5 (purple) M eq of bexarotene (A), UVI3003 (B), MM11253 (C), and adapalene (D). All molecules have induced significant delay in Aβ42 aggregation in CSF.
