Figure 2.

M48 Proteins Are Conserved in Nonphotosynthetic and Photosynthetic Organisms.

Phylogenetic tree of the M48 family based on alignment of amino acid sequences of 92 M48 homologs from diverse archaea, prokaryotes, and eukaryotes. Four clades are assigned: M48A, M48B, M48C, and the new clade M48D. Bootstrap values are indicated at the nodes of the tree. The sequence alignment is shown in Supplemental File 1, and Supplemental Table 1 provides a complete listing of species and number of M48 members. Vitis vinifera (Vvi); Populus trichocarpa (Ptr); Medicago truncatula (Mtr); Brassica rapa (Bra); Arabidopsis thaliana (Ath); Glycine max (Gma); Zea mays (Zma); Brachypodium distachyon (Bdi); Hordeum vulgare (Hvu); Oryza sativa (Osa); Sorghum bicolor (Sbi); Picea sitchensis (Psi); Selaginella moellendorffii (Smo); Physcomitrella patens (Ppa); Cyanidioschyzon merolae (Cme); Chondrus crispus (Ccr); Volvox carteri (Vca); Chlamydomonas reinhardtii (Cre); Chlorella variabilis (Cva); Micromonas pusilla (Mpu); Synechocystis sp PCC6803 (Syne); Anabaena cylindrica (Acy); Nostoc sp PCC7120 (Nos); Synechococcus sp PCC 7942 (Syn); Homo sapiens (Hsa); Penicillium marneffei (Pma); Saccharomyces cerevisiae (Sce); Agrobacterium tumefaciens (Atu); Nitrosomonas europaea (Neu); Escherichia coli (Eco); Sulfuricurvum kujiens (Sku); Streptomyces griseus (Sgr); Bacillus subtilis (Bsu); Leptospira interrogans (Lin); Leptospira biflexa (Lbi); Sulfolobus islandicus (Sis); Metallosphaera sedula (Mse); Haladaptatus paucihalophilus (Hpa); Natrinema pellirubrum (Npe).