Amino acid sequences of XRCC4 from canine (Canis lupus familiaris,
GenBank accession number: LC168634), human (Homo sapiens, GenBank
accession number: AAC50339.1), human isoform (H.sapience-i) (Homo
sapiens, GenBank accession number: NP_071801.1), chimpanzee (Pan
troglodytes, GenBank accession number: XP_001148110.2) and mouse
(Mus musculus, GenBank accession number: NP_082288.1) species. The
location of a putative nuclear localization signal (NLS) sequence in human XRCC4
[21]. Stars mark the location of the SUMO
modification site (K210), polyubiquitylation site (K296) and DNA-PK phosphorylation
sites (S260, S318, S325 and S326) in the human sequences (AAC50339.1)) [20, 32,
34].