Table 5. Results from Final Models^a, presenting Odds Ratios (OR) with 95% Confidence Intervals (95% CI) and P-values, for the Associations between Risk Factors and Severe Lower Respiratory Tract Infection, by Virus Type (HMPV or RSV).

Risk factor	HMPV (n = 171)		RSV (n = 847)
	OR (95% CI)	P	OR (95% CI)	P
Age < 6 months	1.16 (0.23–5.87)	0.853	2.11 (1.33–3.35)	0.002
Age 6–11 months	1.0		1.0
Age 12–23 months	3.01 (0.93–9.75)	0.067	1.19 (0.70–2.00)	0.525
Age ≥ 24 months	3.97 (1.24–12.73)	0.021	1.34 (0.72–2.52)	0.360
Prematureb born	3.36 (1.44–7.83)	0.005	1.58 (1.03–2.42)	0.035
Not premature born	1.0		1.0
≥ 1 chronic disease	2.22 (0.97–5.09)	0.059	2.26 (1.44–3.54)	< 0.001
No chronic disease	1.0		1.0
Ctc < 28	…		7.91 (1.03–61.05)	0.047
Ct 28–35	…		5.33 (0.67–42.59)	0.115
Ct > 35	…		1.0

^aFinal binary logistic regression models, in which HMPV and RSV are analyzed separately. Full models included all factors as age, prematurity, chronic disease, Ct-values and viral co-detection. Factors were stepwise removed when P > 0.1.

^bBorn < 36 gestational weeks.

^cCycle threshold values, a measure of viral load. This factor was not included in the final model for HMPV.

HMPV indicates human metapneumovirus; RSV, respiratory syncytial virus.