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. 2017 Jan 17;12(1):e0163509. doi: 10.1371/journal.pone.0163509

Table 4. The cost-effectiveness of 12- and 24-month HPV testing, compared to 12-month HPV testing only, in women with OHR HPV and cytology ASC-US/LSIL.

Incremental cost-effectiveness ratio (ICER) of 12- and 24-month follow-up compared to 12-month follow-up only (A$/ LYS)
Unvaccinated cohorts Cohorts offered vaccination
12 and 24m follow-up for all ages* $ 238,000 $228,000
12m follow-up for women aged less than 35, then 12 and 24m follow-up for women aged 35+ $147,000 $143,000
12m follow-up for women aged less than 45, then 12 and 24m follow-up for women aged 45+ $97,000 $ 94,000
12m follow-up for women aged less than 55, then 12 and 24m follow-up for women aged 55+ $72,000 $71,000
12m follow-up for women aged less than 65, then 12 and 24m follow-up for women aged 65+ Extended dominated Extended dominated

LYS = life-years saved.

*The ICER for immediate colposcopy for all ages was calculated compared to 12-month follow-up for all ages. If the ICER was instead compared to immediate colposcopy for women aged 35+ years (which was the next most effective strategy), then the calculated ICER increased, and was >$300,000/LYS for both unvaccinated cohorts and cohort offered vaccination.

Extended dominated = the strategy has a higher ICER than a more effective strategy.