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. 2017 Jan 17;12(1):e0169548. doi: 10.1371/journal.pone.0169548

Table 3. Study characteristics.

First author's name Sociodemographic data (Country, type of population, mean age, sex ratio) Sample size Design (time of follow up, number of groups, description of groups) Tool used to assess muscle mass Tool used to assess muscle strength Tool used to assess physical performance Prevalence of sarcopenia Outcomes
da Silva, 2014a[28] Brazil, Community-dwelling adults, Age ≥ 60 years, Age: 69.6 ± 0.6 years, Women: 59.5% 1149 5 years (mean follow-up of 4.19 ± 0.4 years), Two groups: Sarcopenic / Non-sarcopenic Anthropometric equation: Lee equation Hand-held dynamometer Gait speed determined by the walk test of the SPPB (4 m) 15.4% Mortality
da Silva, 2014b[29] Brazil, Community-dwelling adults, Age ≥ 60 years, Age: 68.9 ± 0.4 years, Women: 56.5% 328 4 years, Two groups: Sarcopenic / Non-sarcopenic Anthropometric equation: Lee equation Hand-held dynamometer Gait speed determined by the walk test of the SPPB (4 m) 13.4% Functional disability
Vetrano, 2014[19] Italy, Hospitalized patients, Age ≥ 65 years, Age: 80.8 ± 7 years, Women: 56% In-hospital mortality: 770 / 1-year mortality: 650 1 year, Two groups: Sarcopenic / Non-sarcopenic BIA Hand-held dynamometer Gait speed (4 m) 28% Mortality (in hospital, one-year mortality)
Sanchez-Rodriguez, 2014[20] Spain, Hospitalized patients, Age ≥ 75 years, Age: 84.6 ± 6.6 years (range: 76 to 80.5 years), Women: 61,6% 99 3 months, Two groups: Sarcopenic / Non-sarcopenic BIA Hand-held dynamometer None 46.5% Mortality, Functional status
Sánchez-Rodríguez, 2015[27] Spain, Hospitalized patients, Age ≥ 70, Age: 84,1 ± 8,5 years, Women: 62 (62%) 100 3 months, Two groups: Sarcopenic / Non-sarcopenic BIA Hand-held dynamometer Gait speed (4 m) 58% Functional status, Length of stay
Tanimoto, 2013[33] Japan, Community-dwelling elderly, Age: ≥ 65, Age: Men: 73.3 ± 5.9 years / Women: 73.1 ± 6.2 years, Women: 63,4% (471) 716 2 years Three groups: Sarcopenic / Intermediate / Non-sarcopenic BIA Hand-held dynamometer Gait speed (5 m) 9.36% Functional disability
Arango-Lopera, 2013[30] Mexico, Community-dwelling elderly, Age: ≥ 70, Age: 78.5 ±7 years, Women: 53.3% 345 3 years, Two groups: Sarcopenic / Non-sarcopenic Calf circumference Hand-held dynamometer Gait speed 33.6% Mortality
Landi, 2013[21] Italy, Frail octogenarians living in the community, Age: 80 to 85 years, Age: 82.2 ± 1.4 years, Women: 131 (66.5%) 197 7 years, Two groups: Sarcopenic / Non-sarcopenic Mid-arm muscle circumference (MAMC) Handgrip dynamometer Gait speed (4 m) 21.8% Mortality
Landi, 2012a[22] Italy, Community-dwelling individuals, Age: ≥ 80, Age: 86,7 ± 5.4 years, Women: 177 (68%) 260 2 years, Two groups: Sarcopenic / Non-sarcopenic Mid-arm muscle circumference (MAMC) Handgrip dynamometer Gait speed (4 m) 25.4% Fall
Landi, 2012b[23] Italy, Elderly adults living in a nursing home, Age: ≥ 70, Age: 84.1 ± 4.8 years, Women: 91 (75%) 122 6 months, Two groups: Sarcopenic / Non-sarcopenic BIA Handgrip dynamometer Gait speed (4 m) 32.8% Mortality
Cerri, 2015[24] Italy, Elderly adults hospitalized with malnutrition or at risk of malnutrition, Age: ≥ 65 years, Age: (years) 84.2 ± 7.1 (range: 66–100), Women: 61 (59.2%) 103 3 months, Three groups: Sarcopenic / Non-sarcopenic / Uncertain diagnosis BIA Handgrip dynamometer Gait speed (4 m) 21.4% Mortality
Woo, 2015[34] China, Community-living elderly adults, Age: ≥ 65 years, Mean age: 75,4 years, Women: 246 (55.2%) Varying between 1872 and 4000, depending on the outcome 4–10 years, depending on the outcome of interest, Two groups: Sarcopenic / Non-sarcopenic DXA Handgrip dynamometer Gait speed (6 m), Chair stands 9.02% Mortality, Functional disability, Length of stay
Bianchi, 2015[25] Italy, Community-dwelling elderly adults, Age: ≥ 65 years, Age: 77.1 ± 5.5, Women: 288 (53.5%) 538 55 months (median of follow-up), Three groups: Sarcopenic / Pre-sarcopenic / Non-sarcopenic BIA Handheld dynamometer Gait speed (4 m) 10.2% Mortality, Hospitalization, Functional disability
Chalhoub, 2015[31] USA, Community-living elderly adults, Age: ≥ 65 years, Mean age: 76.8 years, Women: 16.7% (1114), Men: 5544 6658 Men (MrOS): 9 years, Women (SOF): 8 years, 4 groups:Normal BMD, No sarcopenia / Normal BMD, Sarcopenia / Low BMD, No sarcopenia /Low BMD, Sarcopenia DXA Dynamometer Gait speed (6 m) 5.57% Fractures
Saka, 2015[26] Turkey, Nursing home residents, Age: ≥ 65 years, Mean age: 78.0 ± 7.9 years (65–101), Women: 49% (199) 402 1 year, 4 groups: Sarcopenia—MN/MR / Sarcopenia—MN/MR + / Sarcopenia + MN/MR / Sarcopenia + MN/MR + Anthropometric measurements: Calf circumference, Mid-upper arm circumference Handheld dynamometer Gait speed (4 m) 73.3% Mortality
Cawthon, 2015[32] USA, Ambulatory community-dwelling men, Age: ≥ 65 years, Mean age: 76.6 years, 100% men Varying between 3726 and 5934, depending on the outcome 9.8 years, Two groups: Sarcopenic / Non-sarcopenic DXA Handgrip strength - Gait speed (6 m), Average of two trials, Chair stands 4.3% Mortality, Falls, Fractures, Functional limitations
Kim, 2014[35] Korea, Community-dwelling older adults, Age: ≥ 65 years, Mean age: 73.6 years, Women: 48.9% (272) 556 6 years, Two groups: Sarcopenic / Non-sarcopenic DXA Isokinetic device at an angular velocity of 60°/s SPPB score ASM/ht2: 8.8%, ASM/wt: 26% Mortality