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. 2017 Jan 17;12(1):e0170045. doi: 10.1371/journal.pone.0170045

Table 2. Therapy.

Bridging without ASA (n = 181) Bridging with ASA (n = 50) p
Any preexisting antiplatelets, n (%) 62/179 (34.6) 11 (22.0) 0.122
Aspirin, n (%) 48/62 (77.4) 10/11 (90.9)
Clopidogrel, n (%) 13/62 (21.0) 0
Dual Antiplatelet therapy, n (%) 1/62 (1.6) 1/11 (9.1)
Unclear 2 0
Bridging Thrombolysis
IVT
Minutes from onset to start of IVT, mean (range) 164 (58) 166 (58) 0.654
rtPA dose (mg), mean (SD) 51.5 (14.0) 54.2 (14.1) 0.242
ET
Minutes from onset to start of ET, mean (range) 270 (83) 297 (102) 0.102
Mechanical thrombolysis, n (%) 165 (91.2) 47 (94.0) 0.771
Stenting intervention, n (%) 8 (4.4) 36 (72.0) <0.001
Intracranial stenting, n (%) 3 (1.7) 9 (18.0) <0.001
Extracranial stenting, n (%) 5 (2.8) 32 (64.0) <0.001
Administration of Urokinase, n (%) 51 (28.2) 18 (36.0) 0.298
Combined Urokinase and mechanical thrombolysis, n (%) 35 (68.6) 15 (83.3) 0.358
Combined Urokinase and Stenting, n (%) 3 (5.9) 11 (61.1) <0.001
Urokinase dose (IU), mean (SD) 123000 (238000) 154000 (261000) 0.344

Abbreviations: ASA: Acetyl salicylic acid, IVT: intravenous thrombolysis, ET endovascular thrombectomy, SD: standard deviation