. Author manuscript; available in PMC: 2017 Jan 17.

Published in final edited form as: Br J Nutr. 2016 Oct 11;116(8):1416–1424. doi: 10.1017/S0007114516003226

Table 2.

Quartiles of physical activity, alcohol and dietary fat subgroups^*

(Geometric means and 95 % confidence intervals of F₂-isoprostanes (F₂-IsoP) and 2,3-dinor-5,6-dihydro-15-F_2t-isoprostane (15-F_2t-IsoP-M); n 888)

	F₂-IsoP						15-F_2t-IsoP-M
	Unadjusted			Adjusted^†			Unadjusted			Adjusted^†
	Mean	95 % CI	P_trend	Mean	95% CI	P_trend	Mean	95% CI	P_trend	Mean	95 % CI	P_trend
Physical activity (total MET-h/week)			<0·001			0·003			<0·001			0·174
<28·12	1·68	1·57, 1·80		1·60	1·49, 1·71		0·82	0·77, 0·87		0·77	0·72, 0·81
28·12–44·19	1·40	1·31, 1·50		1·41	1·32, 1·51		0·70	0·66, 0·74		0·70	0·66, 0·73
44·20–65·88	1·44	1·35, 1·54		1·46	1·37, 1·56		0·70	0·66, 0·74		0·70	0·66, 0·74
≥65·89	1·26	1·17, 1·35		1·33	1·24, 1·42		0·64	0·61, 0·68		0·69	0·65, 0·72
Alcohol intake (g/d)			0·014			0·086			0·579			0·294
<0·23	1·58	1·47, 1·69		1·56	1·46, 1·67		0·79	0·74, 0·84		0·75	0·71, 1·80
0·23–1·84	1·50	1·39 1·61		1·45	1·35, 1·55		0·73	0·68, 0·77		0·70	0·66, 0·74
1·85–7·99	1·38	1·29, 1·48		1·39	1·30, 1·49		0·66	0·63, 0·70		0·68	0·64, 0·71
≥80	1·33	1·25, 1·42		1·40	1·31, 1·49		0·68	0·65, 0·72		0·72	0·69, 0·76
Total dietary n-6 fatty acids (g)			0·451			0·654			0·726			0·445
<9·43	1·43	1·33, 1·53		1·43	1·34, 1·53		0·73	0·69, 0·78		0·72	0·69, 0·77
9·43–12·63	1·47	1·37, 1·57		1·50	1·40, 1·60		0·68	0·64, 0·72		0·70	0·66, 0·74
12·64–17·43	1·48	1·39, 1·59		1·47	1·37, 1·57		0·72	0·68, 0·77		0·72	0·68, 0·76
≥17·44	1·37	1·28, 1·47		1·39	1·30, 1·49		0·71	0·67, 0·75		0·70	0·66, 0·74
Total dietary n-3 fatty acids (g)			0·306			0·604			0·409			0·226
<1·05	1·45	1·35, 1·55		1·43	1·34, 1·54		0·75	0·71, 0·79		0·73	0·69, 0·78
1 05–1·43	1·52	1·41, 1·62		1·52	1·43, 1·63		0·70	0·66, 0·75		0·71	0·68, 0·75
1·44–1·93	1·41	1·32, 1·51		1·42	1·33, 1·51		0·69	0·65, 0·74		0·70	0·66, 0·74
≥1·94	1·38	1·29, 1·48		1·41	1·32, 1·51		0·70	0·66, 0·75		0·70	0·66, 0·74
SFA (g)			0·091			0·358			0·052			0·564
<13·63	1·39	1·30, 1·49		1·46	1·36, 1·56		0·70	0·66, 0·74		0·72	0·68, 0·76
13·63–18·50	1·42	1·33, 1·52		1·43	1·34, 1·53		0·68	0·64, 0·72		0·69	0·65, 0·72
18·51–25·05	1·40	1·31, 1·50		1·39	1·30, 1·49		0·73	0·68, 0·77		0·72	0·68, 0·76
≥25·06	1·53	1·43, 1·64		1·51	1·41, 1·61		0·75	0·71, 0·79		0·72	0·68, 0·76
MUFA (g)			0·678			0·964			0·858			0·667
<18·06	1·44	1·35, 1·55		1·46	1·36, 1·56		0·72	0·68, 0·77		0·72	0·68, 0·76
18·06–24·37	1·38	1·29, 1·48		1·40	1·31, 1·50		0·68	0·64, 0·72		0·70	0·66, 0·73
24·38–32·86	1·47	1·37, 1·57		1·46	1·37, 1·56		0·72	0·68, 0·77		0·72	0·69, 0·76
≥32·87	1·45	1·36, 1·56		1·47	1·37, 1·57		0·72	0·68, 0·76		0·70	0·67, 0·75
PUFA (g)			0·469			0·676			0·736			0·434
<10·67	1·42	1·33, 1·52		1·43	1·34, 1·53		0·73	0·69, 0·77		0·72	0·68, 0·77
10·67–14·27	1·48	1·38, 1·59		1·51	1·41, 1·61		0·68	0·64, 0·72		0·69	0·66, 0·73
14·28–19·49	1·48	1·39, 1·58		1·46	1·37, 1·56		0·72	0·68, 0·77		0·72	0·68, 0·76
≥19·50	1·37	1·28, 1·46		1·38	1·29, 1·48		0·71	0·67, 0·76		0·71	0·67, 0·75
Trans fat (g)			<0·001			<0·001			<0·001			0·002
<2·94	1·26	1·18, 1·35		1·33	1·25, 1·42		0·64	0·61, 0·68		0·67	0·63, 0·70
2·94–4·36	1·37	1·28, 1·47		1·40	1·31, 1·49		0·67	0·64, 0·72		0·69	0·65, 0·73
4·37–6·24	1·50	1·41, 1·61		1·48	1·39, 1·58		0·74	0·70, 0·78		0·73	0·69, 0·77
≥6·25	1·64	1·53, 1·75		1·58	1·48, 1·69		0·80	0·75, 0·85		0·76	0·72, 0·80
Total fat (g)			0·863			0·860			0·637			0·832
<46·54	1·43	1·34, 1·53		1·45	1·36, 1·56		0·71	0·67, 0·76		0·71	0·68, 0·76
46·55–62·39	1·40	1·31, 1·50		1·42	1·33, 1·51		0·70	0·66, 0·74		0·71	0·67, 0·75
62·40–84·37	1·46	1·36, 1·56		1·47	1·37, 1·56		0·71	0·67, 0·76		0·72	0·68, 0·76
≥84·38	1·45	1·36, 1·56		1·45	1·35, 1·55		0·72	0·68, 0·77		0·70	0·66, 0·74
Total dietary short-chain n-3 fatty acids (g)			0·629			0·824			0·782			0·369
<0·96	1·45	1·35, 1·55		1·44	1·34, 1·54		0·73	0·68, 0·77		0·71	0·67, 0·75
0·96–1·32	1·52	1·42, 1·62		1·53	1·43, 1·64		0·71	0·67, 0·76		0·72	0·68, 0·76
1·33–1·78	1·38	1·29, 1·48		1·39	1·30, 1·48		0·69	0·65, 0·73		0·69	0·66, 0·73
≥1·79	1·41	1·32, 1·51		1·43	1·34, 1·54		0·72	0·68, 0·76		0·71	0·67, 0·76
Total dietary long-chain n-3 fatty acids (g)			<0·001			0·063			<0·001			0·027
<0·05	1·53	1·43, 1·64		1·49	1·40, 1·60		0·77	0·73, 0·82		0·75	0·71, 0·79
0·05–0·08	1·54	1·44, 1·65		1·50	1·41, 1·60		0·74	0·70, 0·79		0·73	0·69, 0·77
0·09–0·15	1·37	1·28, 1·47		1·41	1·31, 1·50		0·69	0·65, 0·73		0·70	0·66, 0·74
≥0·16	1·32	1·23, 1·41		1·39	1·29, 1·48		0·65	0·62, 0·69		0·68	0·64, 0·71
Healthy Eating Index Score^‡			<0·001			0·361			<0·001			0·429
<53	1·53	1·43, 1·65		1·47	1·37, 1·57		0·77	0·73, 0·82		0·72	0·68, 0·76
53–62	1·54	1·44, 1·65		1·51	1·41, 1·61		0·75	0·71, 0·79		0·73	0·69, 0·77
63–71	1·35	1·26, 1·44		1·39	1·30, 1·49		0·68	0·64, 0·72		0·70	0·66, 0·74
≥72	1·34	1·26, 1·44		1·42	1·32, 1·52		0·66	0·62, 0·70		0·70	0·66, 0·74

MET, metabolic equivalent.

Values of F₂-IsoP and 15-F_2t-IsoP-M are expressed in ng/mg creatinine.

^†

Adjusted for age, BMI, race/ethnicity, physical activity, household income, current smoking status, fruit and vegetable servings per day, and any multivitamin and/or supplement use.

^‡

Adjusted for age, BMI, race/ethnicity, physical activity, household income, current smoking status, and any multivitamin and/or supplement use.