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Human AKR Genes Regulated by Nrf2
| gene name | number of AREs based on Nrf2 consensus sequence | positional matrix human LD < 6 | induced by Nrf2 |
|---|---|---|---|
| AKR1A1 | 6 | 5 | X49 |
| AKR1B1 | 1 | 3 | X49 |
| AKR1B10 | 4 | 2 | X49,52,53 |
| AKR1B15 | 4 | 5 | |
| AKR1C1 | 10 | 16 | X7,49,52–54 |
| AKR1C2 | 15 | 24 | X10,49,52,53 |
| AKR1C3 | 4 | 6 | X49,53 |
| AKR1C4 | 2 | 2 | |
| AKR1D1 | 11 | 27 | |
| AKR1E2 | 6 | 3 | |
| AKR6A5 | 26 | 8 | |
| AKR7A2 | 9 | 10 | X51 |
| AKR7A3 | 4 | 4 | X47 |
