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. Author manuscript; available in PMC: 2018 Jan 17.
Published in final edited form as: Chem Res Toxicol. 2016 Nov 16;30(1):162–176. doi: 10.1021/acs.chemrestox.6b00319

Table 3.

Human AKRs and Chemotherapeutic Drug Resistance

Drug Reaction AKR Implicated in Drug Resistance
Cyclophosphamide graphic file with name nihms-833052-t0002.jpg AKR1B10
Daunorubicin graphic file with name nihms-833052-t0003.jpg AKR1A184
Doxorubicin graphic file with name nihms-833052-t0004.jpg AKR1C285
AKR1C385
Oracin graphic file with name nihms-833052-t0005.jpg AKR1C186
AKR1C286
AKR1C386,87