. Author manuscript; available in PMC: 2018 Feb 1.

Published in final edited form as: J Urol. 2016 Oct 5;197(2):391–397. doi: 10.1016/j.juro.2016.09.113

Table 2.

Univariate and multivariate Cox regression models evaluating predictors of disease recurrence

		Univariate Model		Multivariate Model
Characteristic		HR (95% CI)	p-value	HR (95% CI)	p-value
Primary Embryonal	Absent (ref)	-	-	-	-
Primary Embryonal	Present	0.27 (0.14–0.53)	<0.001	0.29 (0.15–0.59)	<0.001
Primary Teratoma	Absent (ref)	-	-	-	-
Primary Teratoma	Present	0.86 (0.4–1.83)	0.693	-	-
IGCCCG risk category	Good (ref)	-	-	-	-
IGCCCG risk category	Intermediate/ Poor	2.24 (1.10–4.54)	0.026	-	-
Second line chemotherapy	No (ref)	-	-	-	-
Second line chemotherapy	Yes	3.62 (1.65–7.93)	0.001	-	-
Post-chemo node size	≤1 cm (ref)	-	-	-	-
Post-chemo node size	>1 cm	3.97 (1.19–13.14)	0.024	-	-
Year of RPLND	1989–1998 (ref)	-	-	-	-
Year of RPLND	1999–2013	0.29 (0.15–0.59)	0.001	0.33 (0.16–0.67)	0.002
RPLND Template	Bilateral (ref)	-	-	-	-
	Unilateral	2.64 (1.29–5.43)	0.008	-	-
	Mass Resection	3.39 (1.33–8.67)	0.011	-	-

HR=hazard ratio; CI=confidence interval; ref=reference; IGCCCG=International Germ Cell Cancer Collaborative Group; RPLND=retroperitoneal lymph node dissection.