Table 1.

Comparison of allele frequencies of 29 EPAS1 SNPs between highland (Sherpa and Tibetans) and lowland populations (CHB, JPT, CEU, and YRI)

Position Chr 2‐GRCh37	SNP ID	Allele		Frequency of derived allele
		Ancestral	Derived	Sherpa (50)	TIB (50)	CHB (97)	JPT (89)	CEU (85)	YRI (88)
46550132	rs116088026	A	C	0.51	0.58	0.00	0.00	0.00	0.06
46552202	rs149594770	T	A	0.54	0.51	0.01	0.00	0.00	0.03
46552352	rs140067727	T	C	0.49	0.51	0.01	0.00	0.00	0.02
46553044	rs113305133	A	G	0.51	0.58	0.01	0.00	0.00	0.03
46565091	rs12614710	G	T	0.52	0.42	0.07	0.04	0.44	0.05
46567916	rs115321619	G	A	0.67	0.74	0.01	0.00	0.01	0.19
46568680	rs73926263	A	G	0.64	0.73	0.01	0.00	0.00	0.07
46569017	rs73926264	A	G	0.67	0.73	0.01	0.00	0.00	0.07
46569770	rs73926265	G	A	0.73	0.73	0.01	0.00	0.00	0.08
46570342	rs55981512	G	A	0.75	0.73	0.01	0.00	0.00	0.04
46571017	rs149306391	C	G	0.75	0.73	0.00	0.00	0.00	0.00
46575388	rs4953354	A	G	0.76	0.79	0.12	0.15	0.18	0.19
46576918	rs76242811	T	C	0.75	0.75	0.01	0.00	0.00	0.10
46577251	rs188801636	T	C	0.74	0.75	0.01	0.00	0.00	0.00
46577299	rs6544889	A	G	0.82	0.81	0.14	0.10	0.54	0.18
46577797	SNP155	T	C	0.76	0.75	—	—	—	—
46583581	rs189807021	G	A	0.74	0.75	0.01	0.00	0.00	0.00
46588019	rs150877473	C	G	0.74	0.75	0.01	0.00	0.00	0.00
46588331	rs142826801	G	C	0.74	0.75	0.01	0.00	0.00	0.00
46589032	rs74898705	C	T	0.74	0.75	0.01	0.00	0.03	0.17
46592807	rs61151542	C	T	0.69	0.74	0.01	0.00	0.03	0.19
46594122	rs141366568	A	G	0.69	0.74	0.01	0.00	0.00	0.00
46597756	rs116062164	A	C	0.69	0.76	0.01	0.00	0.04	0.00
46598025	rs141426873	C	G	0.69	0.74	0.01	0.00	0.00	0.00
46600030	rs116611511	A	G	0.7	0.74	0.01	0.00	0.00	0.10
46600661	rs58160876	A	C	0.7	0.74	0.01	0.00	0.00	0.10
46600894	rs12467821	T	C	0.79	0.78	0.15	0.14	0.52	0.10
46609966	rs11690951	A	T	0.68	0.73	0.20	0.22	0.52	0.06
46615955	rs56161503	G	A	0.68	0.73	0.08	0.10	0.49	0.05