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a) Ribozyme-mediated cleavage curves as determined by 32P data for E6 with S2 (black) and with S3 (red). Fraction cleaved (S/S0) was determined by dividing the amount of cleaved substrate by the sum of the full length and cleaved substrate. b) Ribozyme-mediated cleavage curves as determined by 32P data (red) as well as fluorescence spectroscopy (cyan). See the Supporting Information for additional details.
