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. Author manuscript; available in PMC: 2018 Jan 15.
Published in final edited form as: Clin Cancer Res. 2016 Aug 3;23(2):379–386. doi: 10.1158/1078-0432.CCR-16-1543

Table 2.

Outcomes

Signed Consent (N) 28

Registered 26
Screen Failures (N) 6
  Tissue not available 5
  Tissue not usable 1

Time from consent to tissue availability, days (range)
  All 2.5 (0–21)
  New specimen (N=12) 0 (0–13)
  Archival (N=8) 4.5 (1–21)

Time from biopsy to specimen shipment, days (range) (N=12) 4 (2–7)

Time from specimen shipment to report from FM, days (range) 15.5 (12–30)

Time from report to tumor board, days (range) 5 (3–10)

Recommendation within 28 days of biopsy
  Yes 12 (60%)
  No 8 (40%)

Successful NGS of metastatic biopsy (N) 20

Potentially actionable mutation identified (N) 15

Tumor board recommended targeted therapy as possible next treatment (N) 13

Received targeted therapy as next treatment (4)* 4
*

A patient with an AR+ tumor received bicalutamide on study, a patient with a BAP1 mutation received carboplatin/PARP inhibitor on study, a patient with a MAP2K1 amplification received trametinib off study, and a patient with an ERBB2 mutation received trastuzumab off study.